{"id":69,"date":"2023-06-30T10:52:35","date_gmt":"2023-06-30T13:52:35","guid":{"rendered":"https:\/\/cursaueducacao.com.br\/blog\/?p=69"},"modified":"2024-09-18T13:44:12","modified_gmt":"2024-09-18T16:44:12","slug":"o-que-e-hemostasia","status":"publish","type":"post","link":"https:\/\/cursaueducacao.com.br\/blog\/o-que-e-hemostasia\/","title":{"rendered":"O que \u00e9 hemostasia?"},"content":{"rendered":"\n

Fala biom\u00e9dico, beleza? Voc\u00ea sabe o que \u00e9 hemostasia? Sabe o que essa palavra significa? Antes de mais nada \u00e9 preciso entender que hemostasia<\/strong> N\u00c3O \u00e9 a mesma coisa que homeostase<\/strong>. A homeostase consiste em um processo respons\u00e1vel por manter o organismo em equil\u00edbrio e com todos os seus processos bioqu\u00edmicos, fisiol\u00f3gicos e metab\u00f3licos funcionando. Envolve a regula\u00e7\u00e3o e o equil\u00edbrio da temperatura, press\u00e3o arterial, pH, concentra\u00e7\u00e3o de glicose, entre outras. \u00c9 um mecanismo vital para a sobreviv\u00eancia e o funcionamento adequado do corpo humano. <\/p>\n\n\n\n

E o que \u00e9 a hemostasia ent\u00e3o? Hemostasia \u00e9 o processo pelo qual o organismo interrompe o sangramento ap\u00f3s uma les\u00e3o vascular. Ela acontece em duas etapas e envolve a ativa\u00e7\u00e3o de diversas prote\u00ednas. Vamos entender ent\u00e3o esse processo: <\/p>\n\n\n\n

Primeira etapa: hemostasia prim\u00e1ria<\/strong><\/h4>\n\n\n\n

A hemostasia prim\u00e1ria \u00e9 a primeira resposta ao dano vascular. Ela envolve vasoconstri\u00e7\u00e3o, ades\u00e3o e a agrega\u00e7\u00e3o plaquet\u00e1ria. A vasoconstri\u00e7\u00e3o \u00e9 uma resposta imediata que consiste em contrair a musculatura lisa da parede do vaso, reduzindo o fluxo sangu\u00edneo e minimizando a perda de sangue. Em seguida, as plaquetas s\u00e3o ativadas devido a exposi\u00e7\u00e3o de fatores presentes no endot\u00e9lio, principalmente o fator de von Willebrand. Ap\u00f3s ativa\u00e7\u00e3o, come\u00e7am a se aderir ao endot\u00e9lio e a se agregar, se ligando umas \u00e0s outras, formando um tamp\u00e3o plaquet\u00e1rio no local da les\u00e3o. Esse tamp\u00e3o ajuda a selar a les\u00e3o e iniciar o processo de coagula\u00e7\u00e3o. \u00c9 como se fosse uma rolha que impede o sangue de sair pela abertura que foi feita no vaso.<\/p>\n\n\n\n

<\/h6>\n\n\n\n

Segunda etapa: hemostasia secund\u00e1ria<\/strong><\/h4>\n\n\n\n

Beleza, tudo lindo at\u00e9 ent\u00e3o. Por\u00e9m, n\u00e3o \u00e9 poss\u00edvel parar por aqui. Isso proque as plaquetas n\u00e3o conseguem permanecer aderidas por muito tempo sozinhas e come\u00e7am a se desprender. Para isso, novos mecanismos precisam ser ativados. A hemostasia secund\u00e1ria<\/strong> \u00e9 a fase seguinte da coagula\u00e7\u00e3o, que envolve a forma\u00e7\u00e3o de um co\u00e1gulo mais est\u00e1vel para impedir o resangramento. Para que isso seja poss\u00edvel, precisamos de um elemento a mais junto \u00e0s plaquetas. E esse elemento \u00e9 produzido na cascata de coagula\u00e7\u00e3o. A cascata de coagula\u00e7\u00e3o<\/strong> corresponde \u00e0 uma s\u00e9rie complexa de rea\u00e7\u00f5es bioqu\u00edmicas que resulta na forma\u00e7\u00e3o de fibrina. Se voc\u00ea n\u00e3o sabe como funciona a cascata de coagula\u00e7\u00e3o, clique nesse link<\/a> para conferir.<\/p>\n\n\n\n

A fibrina produzida na cascata de coagula\u00e7\u00e3o forma uma esp\u00e9cie de rede que envolve e estabiliza o tamp\u00e3o plaquet\u00e1rio e sela a les\u00e3o de forma mais duradoura.<\/p>\n\n\n\n

Dist\u00farbios na hemostasia prim\u00e1ria ou secund\u00e1ria podem levar a complica\u00e7\u00f5es hemorr\u00e1gicas ou tromb\u00f3ticas. Por exemplo, defici\u00eancias nos fatores de coagula\u00e7\u00e3o podem resultar em dist\u00farbios de coagula\u00e7\u00e3o, como a hemofilia. Por outro lado, condi\u00e7\u00f5es que promovem a hipercoagulabilidade podem predispor a eventos tromb\u00f3ticos, como trombose venosa profunda ou embolia pulmonar.<\/p>\n\n\n\n

\"a<\/figure>\n\n\n\n

<\/p>\n\n\n\n

Gostou? Conhe\u00e7a nossos treinamentos:<\/h2>\n\n\n\n

Curso de coleta<\/a>
Plataforma cursau<\/a> (com mais de 800H de conte\u00fado e grupo vip)
P\u00f3s gradua\u00e7\u00f5es: micro<\/a>, an\u00e1lises<\/a> e per\u00edcia<\/a><\/h4>\n\n\n\n

<\/p>\n\n\n\n

Refer\u00eancias bibliogr\u00e1ficas:<\/p>\n\n\n\n

KUMAR, V.; et al. Robbins: patologia b\u00e1sica. 9.ed. Rio de Janeiro: Elsevier, 2013. 928 p. <\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Fala biom\u00e9dico, beleza? Voc\u00ea sabe o que \u00e9 hemostasia? Sabe o que essa palavra significa? Antes de mais nada \u00e9 preciso entender que hemostasia N\u00c3O \u00e9 a mesma coisa que homeostase. A homeostase consiste em um processo respons\u00e1vel por manter o organismo em equil\u00edbrio e com todos os seus processos bioqu\u00edmicos, fisiol\u00f3gicos e metab\u00f3licos funcionando. […]<\/p>\n","protected":false},"author":5,"featured_media":116,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9,7],"tags":[],"class_list":["post-69","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-patologia","category-saude-basica"],"yoast_head":"\nO que \u00e9 hemostasia? - Cursau Educa\u00e7\u00e3o - Blog<\/title>\n<meta name=\"description\" content=\"Voc\u00ea sabe o que \u00e9 hemostasia? 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