{"id":219,"date":"2023-07-07T15:26:21","date_gmt":"2023-07-07T18:26:21","guid":{"rendered":"https:\/\/cursaueducacao.com.br\/blog\/?p=219"},"modified":"2024-09-18T13:40:46","modified_gmt":"2024-09-18T16:40:46","slug":"anemia-megaloblastica","status":"publish","type":"post","link":"https:\/\/cursaueducacao.com.br\/blog\/anemia-megaloblastica\/","title":{"rendered":"O que \u00e9 anemia megalobl\u00e1stica?"},"content":{"rendered":"\n

Voc\u00ea estudante da \u00e1rea da sa\u00fade, j\u00e1 ouviu falar em anemia megalobl\u00e1stica? Sabe o que \u00e9 e qual a diferen\u00e7a desse tipo para outros tipos de anemia? Hoje vamos entender as principais caracter\u00edsticas da anemia megalobl\u00e1stica e os mecanismos que desencadeam essa doen\u00e7a. <\/p>\n\n\n\n

Assim como alguns tipos de anemia, a anemia megalobl\u00e1stica \u00e9 caracterizada por uma defici\u00eancia no transporte de oxig\u00eanio para os tecidos. Por\u00e9m, o que difere s\u00e3o os motivos pelos quais esse transprote n\u00e3o \u00e9 eficiente. Veja s\u00f3, em outros tipos de anemia pode haver uma diminui\u00e7\u00e3o da quantidade de hem\u00e1cias ou de hemoglobina. No entanto, no caso da anemia megalobl\u00e1stica, h\u00e1 uma defici\u00eancia na s\u00edntese e amadurecimento correto das hem\u00e1cias. Ou seja, o formato e a fun\u00e7\u00e3o dessas c\u00e9lulas ser\u00e3o prejudicadas, prejudicando por consequ\u00eancia o transporte de oxig\u00eanio. <\/p>\n\n\n\n

<\/h6>\n\n\n\n

<\/p>\n\n\n\n

Vamos entender ent\u00e3o como a anemia megalobl\u00e1stica acontece<\/strong><\/h4>\n\n\n\n

A principal causa desse tipo de anemia \u00e9 a defici\u00eancia de vitamina B12 e\/ou \u00e1cido f\u00f3lico. Ambos s\u00e3o nutrientes essenciais para a forma\u00e7\u00e3o normal das c\u00e9lulas sangu\u00edneas na hematopoiese. Pra ser mais exata, a s\u00edntese de DNA, RNA e prote\u00ednas s\u00e3o processos que dependem de vitamina B12 e \u00e1cido f\u00f3lico para ocorrer corretamente. Alimentos de origem animal, como carne, peixe, ovos e latic\u00ednios s\u00e3o as principais fontes de vitamina B12. O \u00e1cido f\u00f3lico, por sua vez, \u00e9 encontrado em alimentos como vegetais verdes, feij\u00f5es e cereais fortificados. A defici\u00eancia dessas vitaminas pode ocorrer devido a uma m\u00e1 absor\u00e7\u00e3o intestinal ou falta de ingest\u00e3o adequada. <\/p>\n\n\n\n

O resultado dessa defici\u00eancia consiste na matura\u00e7\u00e3o incorreta das hem\u00e1cias durante a eritropoiese, formando c\u00e9lula imaturas chamadas de megaloblastos. Essa \u00e9 uma das principais caracter\u00edsticas da anemia megalobl\u00e1stica, sendo essas c\u00e9lulas maiores do que uma hem\u00e1cia madura, facilmente visualizadas no esfrega\u00e7o sang\u00faineo. Por serem c\u00e9lulas imaturas elas n\u00e3o conseguem transportar oxig\u00eanio adequadamente, resultando em sintomas de anemia. Nesse sentido, a leucopoiese tamb\u00e9m \u00e9 afetada, levando a produ\u00e7\u00e3o de leuc\u00f3citos com o tamanho aumentado, vac\u00faolos no citoplasma e cromatina frouxa.<\/p>\n\n\n\n

Quais s\u00e3o os sintomas da anemia megalobl\u00e1stica? <\/strong><\/h4>\n\n\n\n

Os sintomas podem variar, mas geralmente incluem fadiga, fraqueza, palidez, falta de ar, tonturas e palpita\u00e7\u00f5es. Al\u00e9m disso, algumas pessoas podem apresentar l\u00edngua dolorida e inflamada, perda de apetite, diarreia, icter\u00edcia (colora\u00e7\u00e3o amarelada da pele e dos olhos) e at\u00e9 mesmo sintomas neurol\u00f3gicos, como formigamento nas m\u00e3os e nos p\u00e9s, dificuldade de equil\u00edbrio e falta de coordena\u00e7\u00e3o. Portanto, o tratamento \u00e9 fundamental para prevenir maiores complica\u00e7\u00f5es.<\/p>\n\n\n\n

Gostou? Conhe\u00e7a nossos treinamentos:<\/h2>\n\n\n\n

Curso de coleta<\/a>
Plataforma cursau<\/a> (com mais de 800H de conte\u00fado e grupo vip)
P\u00f3s gradua\u00e7\u00f5es: micro<\/a>, an\u00e1lises<\/a> e per\u00edcia<\/a><\/h4>\n\n\n\n

<\/p>\n\n\n\n

Refer\u00eancias bibliogr\u00e1ficas:<\/p>\n\n\n\n

CARMEL, R. Megaloblastic Anemias. In: HOFFMAN, R. et al. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier, 2018. Cap\u00edtulo 39.<\/p>\n","protected":false},"excerpt":{"rendered":"

Voc\u00ea estudante da \u00e1rea da sa\u00fade, j\u00e1 ouviu falar em anemia megalobl\u00e1stica? Sabe o que \u00e9 e qual a diferen\u00e7a desse tipo para outros tipos de anemia? Hoje vamos entender as principais caracter\u00edsticas da anemia megalobl\u00e1stica e os mecanismos que desencadeam essa doen\u00e7a. Assim como alguns tipos de anemia, a anemia megalobl\u00e1stica \u00e9 caracterizada por […]<\/p>\n","protected":false},"author":5,"featured_media":220,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,7],"tags":[47,19,52,59],"class_list":["post-219","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hematologia","category-saude-basica","tag-biomedicina","tag-diagnostico","tag-hematologia","tag-sintomas"],"yoast_head":"\nO que \u00e9 anemia megalobl\u00e1stica? - Cursau Educa\u00e7\u00e3o - Blog<\/title>\n<meta name=\"description\" content=\"J\u00e1 ouviu falar em anemia megalobl\u00e1stica? Sabe como e porque essa doen\u00e7a acontece? 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