{"id":104,"date":"2023-06-30T11:42:22","date_gmt":"2023-06-30T14:42:22","guid":{"rendered":"https:\/\/cursaueducacao.com.br\/blog\/?p=104"},"modified":"2024-09-18T13:43:56","modified_gmt":"2024-09-18T16:43:56","slug":"exame-de-troponina-ultrassensivel","status":"publish","type":"post","link":"https:\/\/cursaueducacao.com.br\/blog\/exame-de-troponina-ultrassensivel\/","title":{"rendered":"Troponina ultrassens\u00edvel no infarto agudo do mioc\u00e1rdio"},"content":{"rendered":"\n

Durante a gradua\u00e7\u00e3o voc\u00ea com certeza j\u00e1 ouviu falar em infarto agudo do mioc\u00e1rdio (IAM) e dos marcadores card\u00edacos para diagnosticar essa condi\u00e7\u00e3o. A troponina inclusive \u00e9 um desses marcadores. Mas qual \u00e9 a diferen\u00e7a do exame de troponina para o de troponina ultrassens\u00edvel? J\u00e1 ouviu falar nesse tipo de exame? Sabe como realizar e qual a sua import\u00e2ncia no diagn\u00f3stico de IAM? Leia at\u00e9 o final para entender melhor.<\/p>\n\n\n\n

Primeiro de tudo, \u00e9 importante entender que o diagn\u00f3stico precoce e preciso de um IAM \u00e9 crucial para garantir o tratamento adequado e a redu\u00e7\u00e3o de complica\u00e7\u00f5es e de \u00f3bitos. Nesse contexto, os primeiros exames realizados s\u00e3o o eletrocardiograma (ECG) e os exames bioqu\u00edmicos de marcadores card\u00edacos. <\/p>\n\n\n\n

Muitas vezes o resultado do ECG n\u00e3o \u00e9 indicativo de IAM, sendo os marcadores card\u00edacos essenciais para confirma\u00e7\u00e3o do diagn\u00f3stico pelo m\u00e9dico. Da\u00ed entra o exame de troponina ultrasens\u00edvel que surgiu como uma ferramenta revolucion\u00e1ria. <\/p>\n\n\n\n

Por que a troponina ultrassens\u00edvel \u00e9 t\u00e3o importante para o diagn\u00f3stico de IAM?<\/strong><\/h4>\n\n\n\n

A troponina \u00e9 uma prote\u00edna encontrada nas c\u00e9lulas do m\u00fasculo card\u00edaco. <\/p>\n\n\n\n

Durante um infarto, uma obstru\u00e7\u00e3o arterial por placa de ateroma ou trombos, interrompe o fluxo sangu\u00edneo para uma parte do cora\u00e7\u00e3o. Isso resulta em les\u00e3o isqu\u00eamica das c\u00e9lulas card\u00edacas e morte celular por necrose. A troponina \u00e9 liberada na corrente sangu\u00ednea semelhante a outros marcadores como a mioglobina, CK e CKMB, funcionando como marcadores de les\u00e3o card\u00edaca. Contudo, as troponinas apresentam uma maior especificidade para o tecido card\u00edaco.<\/p>\n\n\n\n

A troponina ultrasens\u00edvel nada mais \u00e9 do que uma vers\u00e3o aprimorada do teste tradicional de troponina, sendo capaz de detectar concentra\u00e7\u00f5es extremamente baixas dessa prote\u00edna<\/strong>,. Isso permite um diagn\u00f3stico mais sens\u00edvel e precoce do IAM.<\/strong> Ou seja, mesmo que o paciente esteja infartando h\u00e1 pouco tempo ou a extens\u00e3o da les\u00e3o ainda \u00e9 muito pequena, a concentra\u00e7\u00e3o de troponina no sangue ainda estar\u00e1 muito baixa. Nesse caso, o exame de troponina ultrassens\u00edvel ser\u00e1 capaz de detectar essa prote\u00edna mesmo nessas situa\u00e7\u00f5es devido \u00e0 sua alta sensibilidade.<\/p>\n\n\n\n

Al\u00e9m disso, esse exame \u00e9 altamente espec\u00edfico e ajuda a diferenciar um infarto de outras condi\u00e7\u00f5es card\u00edacas ou n\u00e3o card\u00edacas. Dentre outras caracter\u00edsticas, a troponina ultrassens\u00edvel \u00e9 fundamental para o acompanhamento da les\u00e3o pelo m\u00e9dico, sendo solicitado geralmente a cada 2 ou 3 horas ap\u00f3s a entrada no hospital. \u00c9 ainda capaz de avaliar a gravidade do infarto, o risco de complica\u00e7\u00f5es subsequentes e a monitorar a efic\u00e1cia do tratamento. <\/p>\n\n\n\n

Como realizar o exame de troponina ultrassens\u00edvel?<\/strong><\/h4>\n\n\n\n
    \n
  1. Primeiramente ser\u00e1 feita a coleta da amostra por meio de uma pun\u00e7\u00e3o venosa no tubo de soro<\/strong>.<\/li>\n\n\n\n
  2. Em seguida, a amostra \u00e9 encaminhada para o laborat\u00f3rio para ser processada. Obtem-se ent\u00e3o o soro que \u00e9 onde ser\u00e1 feita a quantifica\u00e7\u00e3o da troponina. <\/li>\n\n\n\n
  3. A t\u00e9cnica empregada \u00e9 a quimiluminesc\u00eancia, uma t\u00e9cnica extremamente sens\u00edvel e capaz de detectar pequenas concentra\u00e7\u00f5es de uma subst\u00e2ncia.<\/li>\n\n\n\n
  4. Os resultados ent\u00e3o s\u00e3o expressos em nanogramas por mililitro (ng\/mL). Os valores de refer\u00eancia giram em torno de < 0,04 ng\/mL. No entando, esses valores variam de laborat\u00f3rio para laborat\u00f3rio visto que ele pode ser ajustado de acordo com uma popula\u00e7\u00e3o espec\u00edfica.<\/li>\n<\/ol>\n\n\n\n

    A partir desses resultados ent\u00e3o, o m\u00e9dico ser\u00e1 capaz de direcionar o melhor tratamento e conduta cl\u00ednica para o paciente.<\/p>\n\n\n\n

    Gostou? Conhe\u00e7a nossos treinamentos:<\/h2>\n\n\n\n

    Curso de coleta<\/a>
    Plataforma cursau<\/a> (com mais de 800H de conte\u00fado e grupo vip)
    P\u00f3s gradua\u00e7\u00f5es:     micro<\/a>, an\u00e1lises<\/a> e per\u00edcia<\/a><\/h4>\n\n\n\n

    <\/p>\n\n\n\n

    Refer\u00eancias bibliogr\u00e1ficas:<\/p>\n\n\n\n

    APPLE, F. S.; LER, R.; MURAKAMI, M. M. Determination of 19 cardiac troponin I and T assay 99th percentile values from a common presumably healthy population<\/a>. Clinical Chemistry, v. 58, n. 11, p. 1574-1581, 2012.<\/p>\n\n\n\n

    APPLE, F. S. et al. Analytical Characteristics of High-Sensitivity Cardiac Troponin Assays<\/a>, Clinical Chemistry<\/em>, v. 58, n. 1, p. 54\u201361, 2012.<\/p>\n","protected":false},"excerpt":{"rendered":"

    Durante a gradua\u00e7\u00e3o voc\u00ea com certeza j\u00e1 ouviu falar em infarto agudo do mioc\u00e1rdio (IAM) e dos marcadores card\u00edacos para diagnosticar essa condi\u00e7\u00e3o. A troponina inclusive \u00e9 um desses marcadores. Mas qual \u00e9 a diferen\u00e7a do exame de troponina para o de troponina ultrassens\u00edvel? J\u00e1 ouviu falar nesse tipo de exame? Sabe como realizar e […]<\/p>\n","protected":false},"author":5,"featured_media":140,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[19,18],"class_list":["post-104","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-profissao-e-carreira","tag-diagnostico","tag-marcadores-cardiacos"],"yoast_head":"\nTroponina ultrassens\u00edvel no infarto agudo do mioc\u00e1rdio<\/title>\n<meta name=\"description\" content=\"Voc\u00ea sabe qual a import\u00e2ncia do exame de troponina ultrassens\u00edvel? 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