{"id":1005,"date":"2024-03-28T15:07:29","date_gmt":"2024-03-28T18:07:29","guid":{"rendered":"https:\/\/cursaueducacao.com.br\/blog\/?p=1005"},"modified":"2024-09-17T16:09:47","modified_gmt":"2024-09-17T19:09:47","slug":"dengue-doenca-e-diagnostico","status":"publish","type":"post","link":"https:\/\/cursaueducacao.com.br\/blog\/dengue-doenca-e-diagnostico\/","title":{"rendered":"Dengue: da doen\u00e7a ao diagn\u00f3stico"},"content":{"rendered":"\n

A dengue \u00e9 uma doen\u00e7a viral transmitida principalmente pelo mosquito Aedes aegypti, que afeta milh\u00f5es de pessoas em todo o mundo, especialmente em regi\u00f5es tropicais e subtropicais. Causada pelo v\u00edrus da dengue, que pertence \u00e0 fam\u00edlia Flaviviridae e possui quatro sorotipos distintos (DENV-1, DENV-2, DENV-3 e DENV-4), essa doen\u00e7a apresenta um espectro cl\u00ednico que varia desde formas assintom\u00e1ticas at\u00e9 quadros graves, como a dengue hemorr\u00e1gica e a s\u00edndrome do choque da dengue, que podem levar \u00e0 morte.<\/p>\n\n\n\n

Os sintomas t\u00edpicos da dengue incluem febre alta, dor de cabe\u00e7a intensa, dores no corpo e nas articula\u00e7\u00f5es, n\u00e1useas, v\u00f4mitos, fadiga e, em alguns casos, erup\u00e7\u00f5es cut\u00e2neas. Esses sintomas geralmente aparecem de 4 a 10 dias ap\u00f3s a picada do mosquito infectado e podem durar at\u00e9 10 dias.<\/p>\n\n\n\n

Com a crescente incid\u00eancia da dengue em diversas partes do mundo, torna-se cada vez mais importante o diagn\u00f3stico precoce e preciso da doen\u00e7a. O diagn\u00f3stico correto n\u00e3o s\u00f3 auxilia no manejo cl\u00ednico adequado dos pacientes, mas tamb\u00e9m contribui para a implementa\u00e7\u00e3o de medidas de controle e preven\u00e7\u00e3o da transmiss\u00e3o do v\u00edrus. <\/p>\n\n\n\n

<\/p>\n\n\n\n

Prof e quais s\u00e3o os exames diagn\u00f3sticos para dengue?
<\/strong><\/h4>\n\n\n\n

Os principais exames diagn\u00f3sticos utilizados atualmente para a dengue s\u00e3o:<\/p>\n\n\n\n

<\/p>\n\n\n\n

Teste NS1:<\/strong><\/h5>\n\n\n\n

O que detecta: Detecta o ant\u00edgeno NS1<\/strong> do v\u00edrus da dengue, sendo eficaz nos primeiros dias de infec\u00e7\u00e3o (1 a 5 dias ap\u00f3s o in\u00edcio dos sintomas).<\/p>\n\n\n\n

R\u00e1pido e pr\u00e1tico, \u00e9 ideal para diagn\u00f3sticos precoces e pode ser realizado em laborat\u00f3rios ou em campo.<\/p>\n\n\n\n

<\/p>\n\n\n\n

Testes Sorol\u00f3gicos:<\/h5>\n\n\n\n

O que detecta: Identificam a presen\u00e7a de anticorpos IgM e IgG <\/strong>no sangue do paciente.<\/p>\n\n\n\n

O IgM \u00e9 geralmente detect\u00e1vel a partir do 4\u00ba dia de infec\u00e7\u00e3o e pode indicar uma infec\u00e7\u00e3o recente, enquanto o IgG \u00e9 detect\u00e1vel ap\u00f3s 7 a 10 dias e indica exposi\u00e7\u00e3o anterior ao v\u00edrus.<\/p>\n\n\n\n

<\/p>\n\n\n\n

Rea\u00e7\u00e3o em Cadeia da Polimerase (PCR):<\/h5>\n\n\n\n

O que detecta: T\u00e9cnica molecular que identifica o material gen\u00e9tico (RNA)<\/strong> do v\u00edrus da dengue.<\/p>\n\n\n\n

Altamente sens\u00edvel e espec\u00edfica, \u00e9 particularmente \u00fatil na primeira semana de infec\u00e7\u00e3o para identificar o sorotipo do v\u00edrus e confirmar o diagn\u00f3stico.<\/p>\n\n\n\n

<\/p>\n\n\n\n

Testes R\u00e1pidos Combinados:<\/h5>\n\n\n\n

O que detecta: Detectam simultaneamente o ant\u00edgeno NS1 e os anticorpos IgM e IgG<\/strong> em uma \u00fanica amostra.<\/p>\n\n\n\n

Oferecem uma abordagem abrangente e r\u00e1pida para o diagn\u00f3stico da dengue, sendo \u00fateis em ambientes com recursos limitados.<\/p>\n\n\n\n

<\/p>\n\n\n\n

Hemograma:<\/h5>\n\n\n\n

Embora n\u00e3o seja espec\u00edfico para dengue, pode indicar altera\u00e7\u00f5es hematol\u00f3gicas como leucopenia (redu\u00e7\u00e3o de leuc\u00f3citos) e trombocitopenia (redu\u00e7\u00e3o de plaquetas), que s\u00e3o comuns na infec\u00e7\u00e3o.<\/p>\n\n\n\n

O diagn\u00f3stico preciso e oportuno da dengue \u00e9 crucial para o manejo adequado da doen\u00e7a e para a preven\u00e7\u00e3o de complica\u00e7\u00f5es graves. \u00c0 medida que a ci\u00eancia avan\u00e7a, novas t\u00e9cnicas e m\u00e9todos diagn\u00f3sticos est\u00e3o sendo desenvolvidos, prometendo maior efic\u00e1cia e rapidez no diagn\u00f3stico desta doen\u00e7a que continua a ser um desafio de sa\u00fade p\u00fablica global.<\/p>\n\n\n\n

<\/p>\n\n\n\n

Colunista,<\/p>\n\n\n\n

Biom\u00e9dico Thiago Nascimento, CRBM 2834<\/p>\n\n\n\n

<\/p>\n\n\n\n

Gostou? Conhe\u00e7a nossos treinamentos:<\/h2>\n\n\n\n

Curso de coleta<\/a>
Plataforma cursau<\/a> (com mais de 800H de conte\u00fado e grupo vip)
P\u00f3s gradua\u00e7\u00f5es: micro<\/a>, an\u00e1lises<\/a> e per\u00edcia<\/a><\/h4>\n\n\n\n

<\/p>\n\n\n\n

Refer\u00eancias:<\/p>\n\n\n\n

Pang J, et al. (2020). The Use of NS1 Rapid Diagnostic Test and qRT-PCR to Complement IgM ELISA for Improved Dengue Diagnosis from Single Specimen. Scientific Reports, 10(1), 7997.<\/p>\n\n\n\n

Fernandez E & Diamond MS. (2021). Vaccination strategies against Zika virus and other flaviviruses. Nature Reviews Immunology, 21(2), 118-133.<\/p>\n\n\n\n

Smith KM, et al. (2022). Rapid detection of dengue virus in saliva by reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay. PLOS ONE, 17(1), e0262172.<\/p>\n\n\n\n

Gupta N & Tripathi S. (2019). Hematological changes in dengue fever: A review. Hematology & Transfusion International Journal, 7(3), 86-90.<\/p>\n","protected":false},"excerpt":{"rendered":"

A dengue \u00e9 uma doen\u00e7a viral transmitida principalmente pelo mosquito Aedes aegypti, que afeta milh\u00f5es de pessoas em todo o mundo, especialmente em regi\u00f5es tropicais e subtropicais. Causada pelo v\u00edrus da dengue, que pertence \u00e0 fam\u00edlia Flaviviridae e possui quatro sorotipos distintos (DENV-1, DENV-2, DENV-3 e DENV-4), essa doen\u00e7a apresenta um espectro cl\u00ednico que varia […]<\/p>\n","protected":false},"author":5,"featured_media":1006,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[37,217,47,168,207,199],"class_list":["post-1005","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saude-basica","tag-analises-clinicas","tag-biomed","tag-biomedicina","tag-biomedico","tag-habilitacao","tag-habilitacoes"],"yoast_head":"\nDengue: da doen\u00e7a ao diagn\u00f3stico - Cursau Educa\u00e7\u00e3o - Blog<\/title>\n<meta name=\"description\" content=\"Hoje vamos aprender sobre a dengue, os principais exames utilizados no diagn\u00f3stico e as caracter\u00edsticas de cada um.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cursaueducacao.com.br\/blog\/dengue-doenca-e-diagnostico\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dengue: da doen\u00e7a ao diagn\u00f3stico - 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